Minimum Effective Volume (MEV 90) of 0.5% Ropivacaine for Ultrasound guided Costoclavicular Block.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Minimum Effective Volume of 0.5% Ropivacaine is calculated by titrating the volume of the drug according to block success or failure in previous patient.Block Success is when Minimal Composite score of 14 out of 16 points achieved(Total Composite score is 16;8 for Sensory and 8 for Motor blockade)Onset of Sensory blockade assessed by cold test(0 no block,1 Analgesia-can feel touch not cold,2 Anaesthesia-cannot feel touch)and Motor blockade by a 3 point scale(0 no block,1 paresis,2 paralysis)
研究概览
简要总结
The purpose of this prospective interventional study is to evaluate the Minimum effective volume of 0.5 % Ropivacaine for Ultrasound guided Costoclavicular block by starting with a defined volume of drug (20 ml)and titrating according to block success(reducing 2 ml for next patient) and block failure(increasing 2 ml for the next patient)
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •All Adults posted for Elbow Forearm Wrist and Hand surgeries ASA grade I/II Body Mass Index 18 to 35 kg /m 2.
排除标准
- •Sepsis or Infection at the site of Injection Pre-existing Peripheral Neuropathy and Coagulation disorder Known Allergy to Local Anaesthetic drugs.
结局指标
主要结局
Minimum Effective Volume of 0.5% Ropivacaine is calculated by titrating the volume of the drug according to block success or failure in previous patient.Block Success is when Minimal Composite score of 14 out of 16 points achieved(Total Composite score is 16;8 for Sensory and 8 for Motor blockade)Onset of Sensory blockade assessed by cold test(0 no block,1 Analgesia-can feel touch not cold,2 Anaesthesia-cannot feel touch)and Motor blockade by a 3 point scale(0 no block,1 paresis,2 paralysis)
时间窗: 8 time points:time 1, immediately after the procedure;time 2,five minutes after completion of the procedure;time 3,ten minutes after the procedure;time 4, fifteen minutes after the procedure;time 5, twenty minutes after the procedure;time 6, twenty five minutes after the procedure;time 7,thirty minutes after the procedure,time 8,thirty five minutes after the procedure
次要结局
- To assess the Onset time of blockade(time from the injection of LA to achieving a Minimal Composite score of 14)and block performance time(Sum of Imaging time-Time interval between contact of USG probe and getting a satisfactory picture plus needling time-From Start of Skin wheal to the end of Local Anaesthetic injection)(8 time points:time 1, immediately after the procedure;time 2,five minutes after completion of the procedure;time 3,ten minutes after the procedure;time 4, fifteen minutes after the procedure;time 5, twenty minutes after the procedure;time 6, twenty five minutes after the procedure;time 7,thirty minutes after the procedure,time 8,thirty five minutes after the procedure)