The Minimum Effective Volume (MEV) of 0.5% Ropivacaine in Ultrasound-guided Supra-anterior Superior Iliac Spine Fascia Iliaca Compartment Block (SASIS-FICB)
Overview
- Phase
- Not Applicable
- Intervention
- Ultrasound-guided Supra-anterior Superior Iliac Spine Fascia Iliaca Compartment Block (SASIS-FICB) with 0.5% ropivacaine
- Conditions
- Nerve Block
- Sponsor
- Peking Union Medical College Hospital
- Enrollment
- 54
- Locations
- 1
- Primary Endpoint
- The MEV90 of 0.5%Ropivacaine in Ultrasound-guided SASIS-FICBS
- Last Updated
- 4 years ago
Overview
Brief Summary
The Aim of This Study is to Determine the Minimum Effective Volume of Local Anesthetic (Ropivacaine 0.5%) Required to Produce an Effective Ultrasound-guided Supra-anterior Superior Iliac Spine Fascia Iliaca Compartment Block（SASIS-FICB） for Surgical Anesthesia in 90% of Patients Scheduled for Elective Surgery of One Lower Limbs.
Detailed Description
The study is based on biased coin design, and the volume of Local Anesthetic (Ropivacaine 0.5%) for the next patient is determined by the result of the last one. In the case of block failure, the volume will be increased by 2.5ml. Conversely, block success will result in either a reduction in volume by 2.5ml (probability 11%) or no change in volume (probability 89%). A blinded assistant will assess sensory and motor blockade in each nerve territory ( the femoral, obturator and lateral femoral cutaneous nerves) at 5-min intervals up to 30 min after completion of the block. Finally, MEV90 is calculated by isotonic regression.
Investigators
Cui Xulei
Associate Professor
Peking Union Medical College Hospital
Eligibility Criteria
Inclusion Criteria
- •patients undergoing hip/knee surgery
Exclusion Criteria
- •age \<18 years
- •body mass index \>35
- •inability to consent to the study
- •allergy to local anesthetics
- •a history of liver or renal insufficiency, coagulopathy
- •clinical evidence of peripheral neuropathies, abnormalities of sensory or motor function of the FN, ON or LFCN.
Arms & Interventions
SASIS-FICB
All subjects will be enrolled in the experimental group and receive an Ultrasound-guided Supra-anterior Superior Iliac Spine Fascia Iliaca Compartment Block (SASIS-FICB)
Intervention: Ultrasound-guided Supra-anterior Superior Iliac Spine Fascia Iliaca Compartment Block (SASIS-FICB) with 0.5% ropivacaine
SASIS-FICB
All subjects will be enrolled in the experimental group and receive an Ultrasound-guided Supra-anterior Superior Iliac Spine Fascia Iliaca Compartment Block (SASIS-FICB)
Intervention: different volume of 0.5% ropivacaine
Outcomes
Primary Outcomes
The MEV90 of 0.5%Ropivacaine in Ultrasound-guided SASIS-FICBS
Time Frame: up to 6 months
We prospectively recruited patients to receive different volumes of SASIS-FICB in accordance with the sequential trial rules of biased coins until 45 successful SASIS-FICB attempts were completed. MEV90 was calculated by isometric regression.