NCT04583033已完成不适用
Lifestyle Stressors of Hippocampus and Alzheimer's Disease (AD) Related Brain Regions: Potential for Intervention
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Rate of brain tissue volume loss in specific brain regions
研究概览
简要总结
The purpose of this study is to slow down the aging of the participant's brain by improving sleep quality.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •English-speaking healthy subjects age 55 years and older capable and willing to consent to participate in the study. In addition, subject should be cognitively normal and have well documented sleep issues that results with poor sleep quality based on self-reported assessment.
排除标准
- •pregnant women
- •cognitively impaired subjects not able to provide consent
- •prisoners
- •Subjects 55 years of age and older that meet criteria for mild cognitive impairment.
- •Subjects with any neurological disorder.
- •Any other condition that in the opinion of the investigator may affect the participation in this study
结局指标
主要结局
Rate of brain tissue volume loss in specific brain regions
时间窗: Year 2
As evaluated from the Magnetic Resonance Imaging (MRI) Brain scan
次要结局
- Cognitive Performance(Year 2)
研究者
Noam Alperin
Professor
University of Miami
研究点 (2)
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