Recovery characteristics after propofol based induction and maintenance of anaesthesia and sevoflurane based induction and maintenance anaesthesia in case of breast Lump Excision
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Time from end of procedure to 1.first spontaneous movement, 2.spontaneous eye
研究概览
简要总结
A surgical procedure performed on a patient admitted and discharged on the same day of surgery is an accepted practice to make hospital resources available for a greater number of patients as each patient gets discharged earlier from the hospital Rapid induction and recovery may lead to faster operating room turnover shorter recovery room stay and earlier discharge to home
Propofol has low lipid solubility and it gets eliminated rapidly from circulation Propofol is proven intravenous anaesthetic agent for day care procedures due to rapid onset of action with early recovery less incidence of post operative nausea and vomiting
Sevoflurane is non inflammable highly fluorinated anaesthetic agent with pleasant smell It is potent hypnotic and fairly non irritant to the upper airway Sevoflurane has low blood gas co- efficient and produces characteristics of fast induction and rapid emergence from anaesthesia Inhalational induction using sevoflurane is rapid smooth and well tolerated in both children and adults
Propofol based anaesthesia is associated with hypotension, bradycardia pain on injection and may have allergic reaction Sevoflurane based anaesthesia provides relatively stable hemodynamics Many studies have been done for phase I recovery but not much work done on phase II recovery with respect to ready for discharge home criteria So we conducted this study to compare recovery profile in both groups Our primary goal was to assess and compare phase I - early recovery time to achieve Aldrete score more than 9 in recovery room as well as phase 2 discharge to home recovery time to achieve PADSS score more than 9 in both the groups
Our secondary goal was to assess and compare induction quality in terms of LMA insertion conditions in both the groups
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 20.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- Female
入选标准
- •ASA 1 and ASA 2 Patient , those who are willing to give informed written consent.
排除标准
- •1.Patient on sedative or opioid medications 2.Psychiatric or neurological disease 3.Susceptible to malignant Hyperthermia 4.Patient with significant cognitive impairment 5.Airway MPG 3 and 4 6.Lack of consent.
结局指标
主要结局
Time from end of procedure to 1.first spontaneous movement, 2.spontaneous eye
时间窗: Outcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
opening
时间窗: Outcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
3.removal of LMA
时间窗: Outcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
4.Followed verbal commands 5.Became fully oriented to
时间窗: Outcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
time and place
时间窗: Outcome assessments will be conducted at baseline pre-anaesthesia, intraoperative period, immediate postoperative period 30 min, 1 hr, 2 hrs, short-term recovery 4 hrs, 8 hrs, and on postoperative day 1 24 hrs after surgery.
次要结局
- 1.Time to achieve Aldrete score more than 9 phase 1 recovery(2.Time to achieve PADSS score more than 9 Phase 2 recovery)