Amikacin Antibiotic prophylaxis in patient with perforation peritonitis :A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 130
- 试验地点
- 1
- 主要终点
- To compare incidence of superficial deep organ space infection in patient receiving amikacin in addition to the standard ceftriaxone and metronidazole with that of patient receiving only the standard protocol following laparotomy for perforation peritonitis
研究概览
简要总结
Surgical site infections encompass a range of superficial to deep wound infections that can occur following an operative procedure. Surgical site infections are preventable complication, responsible for substantial financial burden to health services that can result in poorer patient outcomes,increased mortality, morbidity and reoperation rates.purpose of this study is to explore the usefulness of an antibiotic (injection amikacin) in reducing the occurrence of infections at the site of surgery when used in patient undergoing surgery for perforation peritonitis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •Renal failure Immunosuppressed.
结局指标
主要结局
To compare incidence of superficial deep organ space infection in patient receiving amikacin in addition to the standard ceftriaxone and metronidazole with that of patient receiving only the standard protocol following laparotomy for perforation peritonitis
时间窗: 4 weeks
次要结局
- Surgical site infection, wound dehiscence, readmission, reintervention(4 weeks)
研究者
Subhash Mishra
JIPMER