The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- Mayo Clinic
- 入组人数
- 2,500
- 试验地点
- 1
- 主要终点
- Descriptive Data
研究概览
简要总结
The primary goal of this project is to describe the clinical and physiologic characteristics of Spontaneous Coronary Artery Dissections (SCAD) in order to increase awareness, understanding, treatment and prevention of a potentially fatal cardiovascular event.
This study will be a retrospective and prospective review of medical course and current health of men and women with SCAD.
详细描述
Spontaneous Coronary Artery Dissection (SCAD) is a relatively rare and poorly understood condition that has been reported to affect more women than men. The coronary arteries consist of three layers, and dissection occurs when two of these layers separate, enabling blood to flow into the space between the layers. As the blood accumulates, this can cause obstruction to normal blood flow within the heart, leading to chest pain, heart attack and even sudden death.
The medical community has much to learn about treatment and prevention of this potentially fatal cardiovascular event. Mayo Clinic is conducting two studies of SCAD. This study consists of building a database/registry of patients with SCAD (whether they have been patients at Mayo Clinic or not) to identify patterns of SCAD incidence, causes and associations that could guide future research. With participant consent, Mayo Clinic staff will request a copy of the original coronary angiogram when SCAD was diagnosed to confirm the diagnosis and determine eligibility. If eligible, study coordinators will contact the participant to provide more information about the studies and request a signed informed consent document.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Individuals who have been cared for at Mayo Clinic with a diagnosis of SCAD
- •SCAD in women who are pregnant or within 12 months postpartum at the time of SCAD
- •SCAD in individuals who self-identify as a member of a racial or ethnic group that is currently underrepresented in the registry. This would include anyone who identifies as: Black/African American, Asian, American Indian or Alaska Native, Native Hawaiian or Other Pacific Islander, and any race with Hispanic ethnicity
- •SCAD in a man
- •SCAD in persons younger than 30 years of age
- •SCAD within the past 2 weeks (acute)
- •SCAD patient enrolling into any other Mayo Clinic SCAD Research Study
- •SCAD in individuals who have a relative that has had a SCAD event
- •Persons with history of SCAD who are interested in participating in the study but do not meet the updated inclusion criteria will not be enrolled at this time. However, they will be given the option to share their contact information in order to be invited to future Mayo Clinic SCAD studies.
排除标准
- 未提供
研究组 & 干预措施
SCAD Registry
Individuals who have experienced at least one episode of spontaneous coronary artery dissection.
结局指标
主要结局
Descriptive Data
时间窗: Continuous time frame following index event for 2-10 years from study contact date.
Obtain data regarding SCAD related risk factors, presenting characteristics, treatments and long term outcomes.
次要结局
- Mental Health Update(Continuous time frame following index event for 2-10 years from study contact date.)
- Physical Health Update(Continuous time frame following index event for 2-10 years from study contact date.)
研究者
Marysia Tweet
Principal Investigator
Mayo Clinic