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临床试验/NCT01655589
NCT01655589Unknown不适用

VEGF Gene Polymorphism and Response to Intravitreal Anti-VEGF Agents in Neovascular Age-related Macular Degeneration

Institute of Vision, Brasil1 个研究点 分布在 1 个国家目标入组 74 人开始时间: 2008年1月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
74
试验地点
1

研究概览

简要总结

The main purpose of this study is to investigate the association between VEGF gene polymorphism and the response to intravitreal drugs in neovascular age-related macular degeneration. This is a retrospective review of patients treated between 2008 and 2012 at the Institute of Vision, in Belo Horizonte, Brazil.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
50 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of neovascular age-related macular degeneration
  • Visual acuity better than 20/400
  • Loading dose with three intravitreal injections of anti-VEGF agents, administred one per month over three months
  • Follow-up period of at least six months

排除标准

  • Choroidal neovascularization secondary to any other cause than age-related macular degeneration
  • Eyes with polypoidal choroidal vasculopathy
  • Eyes previously submitted to posterior vitrectomy
  • Other diseases that could affect visual acuity

研究者

发起方
Institute of Vision, Brasil
申办方类型
Other
责任方
Sponsor

研究点 (1)

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