Effects of Ultrasound-guided Recruitment Manoeuvres on Postoperative Pulmonary Complications in OSA Patients Undergoing Total Laparoscopic Hysterectomy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- The lung ultrasound scores of patients after endotracheal intubation (T1), after the first lung recruitment procedure (T2), after the operation (T3), after the second lung recruitment procedure (T4), and 30 minutes after extubation (T5)
研究概览
简要总结
This study aims to evaluate the lung-protective effects of ultrasound-guided lung recruitment maneuvers in patients with OSA undergoing total laparoscopic hysterectomy and to explore the efficacy of EELV measurement in assessing the effectiveness of these maneuvers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years;
- •Scheduled for elective total laparoscopic hysterectomy;
- •American Society of Anesthesiologists (ASA) I to III;
- •BMI > 28 kg/m²;
- •STOP-BANG score ≥ 3.
排除标准
- •Abnormal findings on preoperative chest X-ray or CT, such as atelectasis, pneumothorax, thoracic deformity, pleural effusion, or neuromuscular diseases;
- •Pre-existing severe pulmonary diseases;
- •Severe cardiac arrhythmias or a history of cardiac surgery;
- •Allergy to any medications used in the study.
研究组 & 干预措施
the SRM group
the sustained inflation recruitment maneuver group, n=30
干预措施: the sustained inflation recruitment maneuver (Procedure)
the PRM group
the incremental PEEP recruitment maneuver group, n=30
干预措施: the incremental PEEP recruitment maneuver (Procedure)
the URM group
the Ultrasound-guided recruitment maneuver group, n=30
干预措施: the Ultrasound-guided recruitment maneuver (Procedure)
结局指标
主要结局
The lung ultrasound scores of patients after endotracheal intubation (T1), after the first lung recruitment procedure (T2), after the operation (T3), after the second lung recruitment procedure (T4), and 30 minutes after extubation (T5)
时间窗: Perioperative
次要结局
- Recruitment volume measured by the ΔEELV method(Perioperative)