NL-OMON56247尚未招募不适用
External validation of the beta-lactam target non-attainment (BATMAN) risk score in adult ICU patients: a diagnostic multivariate predictive risk model - BATMA
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 148
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •All patients admitted to the adult general ICU wards and given standard of care
- •intravenous therapy of the target antibiotic are screened for eligibility. In
- •order to be eligible to participate in this study, a subject must meet all of
- •the following criteria:
- •Written informed consent has been obtained from the patient or their legally
- •authorised representative
- •Age >=18 years
- •Treated with one of the following beta-lactam antibiotics at the ICU with
- •intermitted dosage.
- •o Amoxicillin
- •o Amoxicillin with clavulanic acid
- •o Cefotaxime
- •o Ceftazidime
- •o Cefuroxime
- •o Flucloxacillin
- •o Meropenem
- •o Piperacillin with tazobactam
- •Eligible blood material within 36 hours after start of beta-lactam antibiotic
- •to determine target attainment (100%*T > MICECOFF).
- •Suitable intravenous/intra-arterial access to facilitate sample collection
排除标准
- •A potential subject who meets any of the following criteria will be excluded
- •from participation in this study:
- •Written consent has not been obtained
- •<18 years
- •Pregnancy
- •Beta-lactam antibiotic cessation before blood sample collection
- •Receiving beta-lactam antibiotic only as prophylaxis
- •No intravenous/intra-arterial access
- •Patients with renal replacement therapy
- •Patients with burn injury
研究者
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