Macular Changes After Phacoemulsification in Patients with Neovascular AMD
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 主要终点
- To figure out the possibility of Postoperative conversion or relapse ( Dry to wet , wet to reactivated CNV)
研究概览
简要总结
The macula has a very high concentration of photoreceptor cells - the cells that detect light. They send signals to the brain, which interprets them as images. The rest of the retina processes our peripheral, or side vision To explore whether cataract surgery evokes development or relapse of choroidal neovascularization (CNV) in wet age-related macular degeneration (AMD) patients followed for a 1-year postoperative period
详细描述
Age-related macular degeneration (AMD) is a leading cause of vision loss in adults over the age of 50. AMD causes damage to a small part of the retina responsible for central vision called the macula. When damage to the macula occurs, it typically causes loss of central, detailed vision which results in difficulty with tasks such as reading, driving, threading a needle, or recognizing faces.
Phacoemulsification is a modern-day cataract surgery that employs ultrasound energy to emulsify the nucleus, vacuum to catch the nuclear material, and irrigation and aspiration for cortex and viscoelastic removal.
It is currently impossible to draw definitive conclusions whether phacoemulsification (PhE) is safe for people with age-related macular degeneration (ARMD). It is not clear if PhE causes the progression of ARMD and affects visual acuity (VA). The purpose was to analyze the possible association of PhE with ARMD progression in the early and late (up to 18 months after surgery) period.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects included in this study aged above 50 and presented for routine check up after undergoing phacoemulsification:
- •Above 50 years old
- •not diabetic individuals
排除标准
- •intraoperative complications
- •Eyes with diseases predisposing them for postoperative macular edema, preexisting macular edema, and eyes that developed cystoid macular edema
- •active ocular inflammation or infection _glaucoma
- •A preoperatively worsened VA regardless phE
- •ocular trauma
- •patients with central retinal ischemia
- •previous vitrectomy
结局指标
主要结局
To figure out the possibility of Postoperative conversion or relapse ( Dry to wet , wet to reactivated CNV)
时间窗: baseline
To explore whether cataract surgery evokes development or relapse of choroidal neovascularization (CNV) in wet age-related macular degeneration (AMD) patients followed for a 1-year postoperative period
次要结局
未报告次要终点
研究者
Demiana alkes zakka labib
doctor
Assiut University