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临床试验/NCT01745042
NCT01745042已完成不适用

Impact of Fat Distribution on Metabolic, Cardiovascular and Symptomatic Aspects in Postmenopausal Women

University of Sao Paulo1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2009年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
45
试验地点
1
主要终点
Relationships between postmenopause and fat distribution

研究概览

简要总结

The purpose of this study is to investigate anthropometric, metabolic, cardiovascular and symptomatic profiles in postmenopausal women.

详细描述

When aging, the body composition changes, leading to a reduction of muscle mass and strength, and to an increase in total body fat. These body composition changes have especially been observed in postmenopausal women, due to the hormonal changes taking place. After the menopause, the gynoid fat distribution with fat deposits in the gluteo-femoral region changes to an android fat distribution with an increased upper body fat, especially in the abdominal region. These consequences of the menopause associated with a decrease in aerobic capacity and reduced total energy expenditure may lead to the metabolic syndrome (MetS). The aim of this study was to investigate the anthropometric, metabolic, cardiovascular and symptomatic profile in gynoid and android postmenopausal women.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
50 Years 至 60 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Postmenopausal women
  • Caucasian
  • 50-60 years of age

排除标准

  • Neurological disease
  • Pulmonary disease
  • Cardiac disease
  • Oncological disease
  • Musculotendinous or articular injuries
  • Hormone replacement therapy
  • Cigarette smoking

结局指标

主要结局

Relationships between postmenopause and fat distribution

时间窗: Baseline

Anthropometric measurements: waist-to-hip ratio and body mass index

次要结局

  • Comparison of the body composition between android and gynoid postmenopausal women(Baseline)
  • Comparison of metabolic parameters between android and gynoid postmenopausal women(Baseline)
  • Comparison of quality of life between android and gynoid postmenopausal women(Baseline)
  • Comparison of aerobic capacity between android and gynoid postmenopausal women(Baseline)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Fernanda Rossi Paolillo

Federal University of São Carlos

University of Sao Paulo

研究点 (1)

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