Prospective Study to Obtain Preliminary Data to Determine the Efficacy of Non Contrast DWI Imaging Compared to CMR-DE
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- presence and apparent diffusion coefficient (ADC) quantification of scar on (DWI) diffusion weighted image
研究概览
简要总结
Use of MRI and DWI to diagnose cardiac scarring after heart attack.
详细描述
To discover new information about MRI (magnetic resonance imaging) called DWI (diffusion weighted imaging) and its ability to diagnose cardiac scarring.
CMR-DE (cardiac MR with delayed contrast enhancement) evaluates if there has been scarring in the heart muscle following a heart attack.
Subjects are injected with a contrast medication that makes the scarring visible if present. To prove the efficacy of DWI (diffusion weighted imaging) to provide the same images that CMR-DE (cardiac magnetic resonance with delayed contrast enhancement) provides.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Males and females 21 years of age and older
- •Healthy volunteers
- •subjects with a prior history of heart attack and prior CMR-DE imaging.
排除标准
- •Women who are pregnant
- •Subjects with GFR < 60 ml/min/1.73m2
- •Subjects with ICD
- •Subjects with coronary stents incompatible with 3T
结局指标
主要结局
presence and apparent diffusion coefficient (ADC) quantification of scar on (DWI) diffusion weighted image
时间窗: single occurance
Confirm the efficacy of diffusion weighted imaging in providing imaging that shows cardiac scarring without the injection of contrast.
次要结局
未报告次要终点
研究者
Jadranka Stojanovska, M.D.
Principal Investigator
University of Michigan