NCT02457572已完成不适用
Pulse Pressure Variation Measured During Valsalva Maneuver to Predict Fluid Responsiveness Under Open-chest Condition in the Patients Undergoing Off-pump Coronary Arterial Bypass Grafting
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- Pulse pressure variation during Valsalva maneuver
研究概览
简要总结
Pulse pressure variation (PPV) is a well-known dynamic preload indicator to predict fluid responsiveness. However, its usefulness in open-chest conditions has been equivocal. The investigators evaluated whether PPV measured during Valsalva maneuver can predict fluid responsiveness after sternotomy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients undergoing elective off-pump coronary arterial bypass grafting
排除标准
- •Preoperative LV EF <= 35%
- •Moderate or severe valvular heart disease
- •Cardiac arrhythmia
- •Intracardiac shunt
- •Severe renal or liver disease
- •Moderate to severe pulmonary hypertension (mean PAP > 35 mmHg)
- •Patients with bullous lung disease or combined pneumothorax
结局指标
主要结局
Pulse pressure variation during Valsalva maneuver
时间窗: during Valsalva maneuver
次要结局
- Pulse pressure variation after sternotomy(5 min after sternotomy)
研究者
Jong Hwan Lee
Assistant professor
Samsung Medical Center
研究点 (1)
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