Proteins and salivary metabolites related to Periodontitis and Gestational Diabetes Mellitus during the 3rd trimester of pregnancy

Faculdade de Odontologia de Bauru - Universidade de São Paulo0 个研究点开始时间: 2024年6月5日最近更新: 2024年6月25日

适应症

试验速览

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•Pregnant women who are in the 3rd trimester of pregnancy (from the 27th gestational week); between 18 and 40 years of age; with regular follow-up with the obstetrician; who have already undergone the Oral Glucose Tolerance Test through the Unified Health System between the 24th and 28th week of pregnancy, as recommended by the World Health Organization; and who present adequate cognitive and neuromotor behavior, enabling easy understanding for participation in the research and adequate ability to perform regular oral hygiene

•Participants who have systemic arterial hypertension (blood pressure equals to or higher than 140/90 mmHg) diagnosed before or during pregnancy will be excluded from the sample; pre eclampsia; malnutrition (pre-pregnancy Body Mass Index [BMI] lower than 18.50 kg/m2); obesity (pre-pregnancy BMI equals to or higher than 30.00 kg/m2); diagnosed or suspected of being infected with SARS-CoV-2; who require absolute rest for any medical reason; diagnosed with any other systemic disease other than Gestational Diabetes Mellitus; who are using, or who have used at any time during pregnancy, antibiotics or any medication that may interfere with periodontal condition and/or salivary flow (for example, immunosuppressive drugs, anticonvulsants or calcium channel blockers, such as cyclosporine, phenytoin or nifedipine, respectively), with hyposalivation (flow lower than 0.25 ml/min); diagnosed with stage I periodontitis; who have one or more cavitated carious lesions; with multiple tooth loss (more than two teeth per hemiarch); with tooth loss prior to pregnancy due to periodontitis; who are undergoing orthodontic, periodontal treatment or with another dental surgeon with a treatment plan already determined; who have previously undergone surgical periodontal treatment; users of alcohol/tobacco/illegal drugs during pregnancy

发起方

Faculdade de Odontologia de Bauru - Universidade de São Paulo