Relationship Between Serum N/OFQ and Acute Myeloid Cell Leukemia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- N/OFQ
研究概览
简要总结
Patients diagnosed with acute myeloid leukemia in the Second Hospital of Shanxi Medical University were selected and divided into the newly diagnosed group, the relapsed group, the complete remission group as the experimental group, and the healthy physical examination subjects as the control group. The relationship between IL-1β, catecholamine and norkephalin in peripheral blood of the experimental group and the control group was observed. According to the literature, the experimental group was significantly higher than the control group. In the experimental group, the newly diagnosed group was higher than the relapse group, and the relapse group was higher than the complete remission group, and the correlation was positive, and the difference was statistically significant.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •In accordance with adult acute myeloid leukemia (non-acute promyelocytic leukemia)The diagnostic criteria for AML in the Chinese Diagnosis and Treatment Guidelines (2017 edition); ②Leukocyte count ≤ 25×109/L;
- •No treatment has been received in the past 6 months.
- •None of the candidates are related and known this study, and sign the informed consent.
排除标准
- •Patients who are allergic to the drugs used in this study;
- •People with mental illness or cognitive impairment;
- •Patients with infectious diseases; ④Patients with severe heart, liver, kidney and other organ function lesions; ⑤ Combined with other malignant swelling. The tumor.
结局指标
主要结局
N/OFQ
时间窗: 24 hours
Serum N/OFQ levels
NE
时间窗: 24 hours
Serum NE levels
IL-1β
时间窗: 24 hours
Serum IL-1β levels
次要结局
未报告次要终点
研究者
Zheng Guo
professor
Second Hospital of Shanxi Medical University