Relationship Between Serum N/OFQ and Cerebral Cardiac Syndrome After Stroke
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- NE
研究概览
简要总结
Choosing the neurology patients in the Second Hospital of Shanxi Medical University, diagnosed with patients with cerebral syndrome into the experimental group; patients who did not have cerebral syndrome included in the control group, and all selected people had no intimate relationship with each other.Specimen collecting control group and the study group serum inflammatory factor IL-6, solvent peptide and catecholamine content. The difference between the two groups of data was observed.According to the literature, it is guess: The solitary peptide content of the experimental group will be higher than the control group, and is positively correlated with IL-6, catecholamine content.The difference was statistically significant.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnostic criteria in compliance with cerebral syndrome
- •Acute ischemic stroke patients in line with the "Chinese Acute Ischemic Stroke Treatment Guide 2018" related diagnostic criteria
- •There is no intimate relationship between all selected people and knows this study, and signs informed consent
排除标准
- •Heart-type cerebral infarction, hemorrhagic stroke, brain tumor and past intracranial hemorrhage
- •Complicated with severe cardiovascular complications (such as coronary heart disease, acute coronary syndrome, acute myocardial infarction, chronic heart failure, atrial fibrillation, etc.)
- •Complicated with severe liver and kidney dysfunction (such as coagulous dysfunction, cirrhosis, nephrotic syndrome , Renal failure, etc.)
- •Complicated with severe diabetes complications (such as diabetic nephropathy, diabetic foot, diabetic acidosis, high blood sugar hypertonic state, diabetes coronary heart disease, etc.)
- •Complicated with Psychological disease
- •Complicated with chronic obstructive pulmonary disease(COPD)
结局指标
主要结局
NE
时间窗: 24 hours
Serum NE levels
N/OFQ
时间窗: 24 hours
Serum N/OFQ levels
IL-6
时间窗: 24 hours
Serum IL-6 levels
次要结局
未报告次要终点
研究者
Zheng Guo
professor
Second Hospital of Shanxi Medical University