跳至主要内容
临床试验/jRCT1060240100
jRCT1060240100进行中(未招募)不适用

Clinical Effects of Ubiquinol (Reduced Coenzyme Q10) for Dementia: Additional Analysis

未提供0 个研究点目标入组 27 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
27
主要终点
Neuropsychological tests

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
50age old over 至 89age old under(—)

入选标准

  • Any of the following five types of dementia patients,
  • Alzheimer's disease dementia
  • Vascular dementia
  • Dementia with Lewy bodies
  • Frontotemporal dementia

排除标准

  • Has a comorbid metabolic disorder (e.g., hypothyroidism, vitamin B12 deficiency).
  • Has a history of head trauma.
  • Exhibits symptoms of delirium caused by medication.
  • Is dependent on alcohol.
  • Has comorbid depression being treated with antidepressants.
  • Is receiving treatment with antipsychotic medications for psychiatric symptoms (e.g., confusion, hallucinations, delusions, or abnormal behavior).
  • Has comorbid schizophrenia, mania, severe cardiac disease, or liver disease.
  • Has impaired renal function with a creatinine clearance (Ccr) of 20 ml/min or less.
  • Is undergoing treatment for malignant tumors.
  • Is deemed unsuitable for participation in this study by the principal investigator.

结局指标

主要结局

Neuropsychological tests

时间窗: before and 12 months after administration

MMSE, Hasegawa Dementia Scale, Motivation Score, Self-Rating Depression Scale, Frontal Lobe Function Test, and ADAS-Jcog

次要结局

未报告次要终点

研究者

发起方
未提供

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