A Retrospective Analysis of Neck Dissection Following Complete Response to Chemoradiation in HNSCC
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 165
- 试验地点
- 3
- 主要终点
- Overall survival
研究概览
简要总结
RATIONALE: Gathering disease-related information from medical charts of patients with primary head and neck cancer who have undergone neck dissection after complete response to chemotherapy and radiation therapy may help doctors learn more about the disease and find better methods of treatment.
PURPOSE: This clinical trial is evaluating the medical charts of patients with primary head and neck cancer who have undergone neck dissection after complete response to chemotherapy and radiation therapy.
详细描述
OBJECTIVES:
- Perform a retrospective analysis, by medical chart review, of patients with primary squamous cell carcinoma of the head and neck who underwent neck dissection following complete response to chemoradiotherapy.
- Determine whether the role of a post-chemoradiotherapy neck dissection affects the outcome of the patient's disease, in terms of overall survival, disease-free survival, and recurrence rates.
OUTLINE: This is a pilot, retrospective study.
Patients who have undergone neck dissection after achieving a complete clinical and radiological response to chemoradiotherapy are compared to patients who did not. Data are gathered by medical chart review.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of primary squamous cell carcinoma of the head and neck at any of the following sites:
- •Oral cavity
- •Oropharynx
- •Hypopharynx
- •Complete response achieved after treatment with chemoradiotherapy
排除标准
- •Not specified
- •PRIOR CONCURRENT THERAPY:
- •See Disease Characteristics
结局指标
主要结局
Overall survival
时间窗: off-study date
次要结局
- Disease-free survival(off-study date)
- Recurrence rate(off-study date)
研究者
Barbara Murphy, MD
Professor of Medicine; Director, Cancer Supportive Care Program; Director, Head and Neck Research Program; Medical Oncologist
Vanderbilt-Ingram Cancer Center