Serum Elafin :A Biomarker in Behcet Disease and Its Relation to Vascular Involvement and Disease Activity
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 主要终点
- To measure the level of serum elafin in behcet patients and compare it with control group
研究概览
简要总结
To measure the level of serum elafin in patients with behcet disease and to assess the correlation between serum elafin and vascular affection and their relation with disease activity
详细描述
Behcet disease is a chronic multi systemic inflammatory disease characterized by recurrent oral and genital ulcers and multiple systemic affection . Elafin is a serine protease inhibitor produced mainly by epithelial cells . previous studies documented the role of serum elafin in pathogenesis of behcet disease.vascular complications may be one if the earliest manifestation leading to the diagnosis of behcet disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients diagnosed as behcet disease Age (20-45)
排除标准
- •age <20 and >45 Other autoimmune diseases Risk factors (ischemic heart disease, diabetes) Chronic conditions (malignancy, chronic kidney disease)
结局指标
主要结局
To measure the level of serum elafin in behcet patients and compare it with control group
时间窗: Within 1year
Measure the level of serum elafin in behcet and its relation to disease activity and vascular involvement
次要结局
未报告次要终点
研究者
Lobna Amer Araby Ahmed
Assuit
Assiut University