NCT01628276已完成不适用
Brain Functional Connectivity Changes Following Cognitive Rehabilitation in Multiple Sclerosis: an fMRI Study
Sina Hospital, Iran1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2012年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- functional connectivity
研究概览
简要总结
This trial seeks to investigate brain network changes following cognitive rehabilitation in MS patients. The investigators hypothesize that rehabilitation interventions improve connectivity in the brain.Novel Magnetic Resonance Imaging technique is performed to investigate changes in brain plasticity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 54 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Definitive MS diagnosis
- •Right handedness
- •No relapse in past 6 weeks
- •Willing to consent and participate in the study
排除标准
- •Pregnancy
- •Left handedness
- •Neurologic or psychiatric disorder other than MS
结局指标
主要结局
functional connectivity
时间窗: 0, 2nd, 4th Month
Changes in correlation of brain activity in different regions of brain as assessed by Blood Oxygenation Level Dependent (BOLD) signal
次要结局
未报告次要终点
研究者
Mohammad Ali Sahraian
Vice President
Sina Hospital, Iran
研究点 (1)
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