CTRI/2024/08/072292尚未招募3 期
Olanzapine versus Aprepitant for prevention of chemotherapy induced nausea and vomiting in children receiving highly emetogenic chemotherapy: A Randomized Open Label Trial - Nil
Dr Nikita Jakhar0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Confirmed diagnosis of malignancy
- •2. Scheduled for highly emetogenic chemotherapy
- •3. Should be able to swallow the drug
- •4. Written informed consent
排除标准
- •1. Have had treatment within 14 days prior to study enrolment with olanzapine or 30 days prior with another antipsychotic agent
- •2.Planned to receive quinolone antibiotics or other antipsychotic agents, citalopram, amifostine, CYP1A2 inducers or inhibitors
- •3. History of seizure disorder
- •4. History of hypersensitivity to olanzapine
- •5. Vomited in the prior 24 hours to first dose of chemotherapy
- •6.Abnormal lab values (absolute neutrophil count less than 1000/mm3, total leucocyte count less than 3000/mm3, platelet count less than 100,000mm3, AST/ALT more than 2.5 times of upper limit of normal, total serum bilirubin more than 1.5 times of upper limit of normal and serum creatinine more than 1.5 times of upper limit of normal)
- •7. Steroids within 24 hours prior to enrolment
研究者
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