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临床试验/NCT05584358
NCT05584358已完成不适用

The Impact of the Extrusion Process During Dietary Protein Production on in Vivo Postprandial Amino Acid Availability

University of Exeter4 个研究点 分布在 1 个国家目标入组 9 人开始时间: 2022年2月2日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
9
试验地点
4
主要终点
Plasma amino acid concentrations

研究概览

简要总结

The bulk of research that has investigated the effect of dietary protein on muscle tissue in humans has used isolated, minimally processed protein powders. However, the protein that we consume on a daily basis has typically undergone various processing methods, and evidence suggests these can change the way our bodies metabolise the protein. 'Extrusion' is a common processing method that uses high pressure to produce protein containing cereals and meat replacement foods. There is currently no research looking at how extrusion affects the way a protein source is digested and absorbed in humans. This study will compare the availability of ingested protein in the blood in the hours following consumption of an extruded versus a non-extruded source.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • BMI between 18 and
  • Metabolically healthy

排除标准

  • Any metabolic impairments
  • cardio/pulmonary diseases.
  • Chronic use of the over the counter medicine
  • A personal or family history of epilepsy, seizures or schizophrenia.
  • Allergic to mycoprotein/Quorn/edible fungi/environmental mould products.

结局指标

主要结局

Plasma amino acid concentrations

时间窗: 5 hours

The rate of appearance of amino acids ingested in the drink

次要结局

  • Blood glucose(5 hours)
  • Resting metabolic rate(5 hours)
  • Serum insulin(5 hours)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (4)

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