DYNAMIC STRESS PERFUSION CT FOR DETECTION OF INDUCIBLE MYOCARDIAL ISCHEMIA - SPECIFIC trial

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 70 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•* Age > 21 years
•* Stable angina symptoms, suspected or known CAD, and referred for invasive angiography on clinical grounds.
•* Ability to provide informed consent
•* Ability to perform a 20-30 second breath hold

•* Hemodynamically and clinically unstable condition (angina at rest, malignant arrhythmias)
•* Prior, documented myocardial infarction, other than (procedure related) minor type II myocardial infarction, which includes Q waves on the ECG or evidence of myocardial infarction on prior non-invasive imaging.
•* Coronary artery bypass graft surgery or primary PCI for acute myocardial infarction.
•* Significant other cardiovascular conditions affecting the interpretation of MPICT, including, but not limited to: clinical heart failure, IECD (pacemaker/ICD), severe valvular heart disease or prosthetic valves, significant intra-cardiac shunting or other relevant congenital heart disease.
•* eGFR<60 ml/kg/min
•* BMI>35 kg/m2
•* Atrial fibrillation or other arrhythmia, >6 ectopic beats / min
•* Known or suspected allergy to iodinated contrast medium
•* Pregnancy cannot be excluded
•* Contra-indications for adenosine: bronchial asthma, second or third degree atrioventricular block, blood pressure <110/70 mmHg, allergies or severe side effects in the past.

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