临床试验/NCT00622934

NCT00622934Unknown2 期

Relationship Between Clinical Recovery and Oxidative Stress and Inflammation Following Usage of Erythropoietin in Admitted Traumatic Patient In Intensive Care Unit

Tehran University of Medical Sciences1 个研究点分布在 1 个国家目标入组 20 人开始时间: 2007年7月最近更新: 2010年11月18日

适应症

干预措施

试验速览

阶段: 2 期
发起方: Tehran University of Medical Sciences
入组人数: 20
试验地点: 1
主要终点: apachi 2 saps 30 days mortality

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to determine whether Erythropoietin decrease stress responses and inflammation in trauma patient.

详细描述

Transfusion of blood products has many disadvantages. Erythropoietin is used to increase red blood cells production and decrease such disadvantages.In some studies anti inflammatory effects is shown for Erythropoietin.

One of the most problems in the intensive care unit is stress response. we are going to evaluate effects of erythropoietin on oxidative stress and inflammation in trauma patient in intensive care unit.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围: 40 Years 至 65 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•All multiple trauma patients>16 years with informed consent

排除标准

•Hypertension
•Erythroid leukemia
•Pregnancy and breast feeding
•Pre operative patient
•Severe cardiovascular and cerebrovascular diseases
•Thromboembolic disorders

研究组 & 干预措施

1

Active Comparator

干预措施: erythropoietin (Drug)

2

Placebo Comparator

干预措施: placebo (Drug)

结局指标

主要结局

apachi 2 saps 30 days mortality

时间窗: untill discharge

次要结局

30 days mortality(30 days)

研究者

发起方

Tehran University of Medical Sciences

申办方类型

Other

研究点 (1)

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