Association Between Blood Glucose Indicators and Heart Rate Variability in Non-diabetic Critically Ill Patients: a Single-center Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Correlation between glucagon and HRV in non-diabetic critically ill patients
研究概览
简要总结
Heart rate variability (HRV) is a simple way to check how well the body's automatic nervous system is working. It does this by looking at how the heart rate changes in the electrocardiogram. HRV can be divided into time domain and frequency domain. Time domain indicators assess the tone of the autonomic nerves. Frequency domain indicators reflect the regulation of the sympathetic and parasympathetic nerves. An imbalance of the body's nervous system can be reflected by HRV. Stress hyperglycemia (SIH) is when your blood glucose levels go up because of an acute disease. This is usually related to the body's stress response, but if your blood glucose levels go up too much, it can lead to complications. A high blood sugar level caused by stress is common in intensive care units. There is a strong link between this and the death rate and how long patients stay there. There are lots of nerve endings in the pancreas. Nerve fibres control the way islet α/β cells work to keep the right amount of glucose in the blood. We know that the pancreatic nerve is important for controlling blood glucose levels, but we don't fully understand how it does this.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged from 18 to 99 years old
- •Informed consent has been signed
排除标准
- •Under 18 years old
- •Diagnosed with diabetes either prior to or during hospitalization
- •Missing HRV values
- •Missing blood glucose and random insulin values
结局指标
主要结局
Correlation between glucagon and HRV in non-diabetic critically ill patients
时间窗: From enrollment to completion of indicator testing (within 24 hours)
次要结局
- The correlation between blood glucose and random insulin levels and HRV in non-diabetic critically ill patients(From enrollment to completion of indicator testing (within 24 hours))
