Appendicular Skeletal Muscle Mass Adult Reference Measurements in Greek Population
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Appendicular skeletal muscle mass reference measurements of healthy young adults in Greece
研究概览
简要总结
There is a lot of discussion concerning the normal cut-off points of skeletal mass among different populations worldwide. Genetic and environmental differences most probably lead to different measurements. Defining muscle mass in healthy young adults in Greece will provide information that can be used to determine normal ranges of muscle mass of both sexes and consequently define sarcopenia.
The aim of the study is to define appendicular skeletal muscle mass reference measurements in healthy young adults in Greece. These values can be used to determine sarcopenia cut-offs according to recommendations.
详细描述
Introduction
The reduction of muscle mass in humans is obvious after the age of fifty, with a reduction rate of 3-8% every ten years. The rate of loss accelerates with chronic diseases, sedentary lifestyle, low physical activity, nutritional, environmental and socioeconomic factors .
Sarcopenia has been officially recognized as a disease according to World Health Organization. European Working Group on Sarcopenia in Older People 2 has revised the definition and diagnostic criteria of sarcopenia aiming to encourage more research in the field. In Greece, there are no reference values for muscle strength and muscle mass. Defining these values will permit the investigators to provide a tool that will help to establish country - specific measurements of sarcopenia in Greek population.
Study population-Methods
The study site will be the Outpatient Geriatric Assessment Unit and the Radiology Department of Henry Dunant Hospital Centre, in Athens-Greece.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 44 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy Greek young adults (20 - 44 years old), with Caucasian characteristics.
- •Able to read and write in Greek language.
排除标准
- •Chronic diseases, such as, heart diseases, type II diabetes mellitus and autoimmune diseases.
- •Hyperthyroidism or hypothyroidism (persons with normal thyroid function for six months are included).
- •Malignancies.
- •Seizures of epilepsy, neurodegenerative diseases.
- •Asthma and/or chronic respiratory pulmonary disease-Chronic Obstructive Pulmonary Disease.
- •Metal prefixes.
- •Systematic medication intake (such as hypolipemic drugs, antihypertensive drugs, antidepressants, glucocorticoids and any other hormonal treatment).
- •Protein formulations and anabolic intake.
- •Hormone intake (testosterone, estrogen, contraceptive, growth hormone, dehydroepiandrosterone.
- •Professional athletes and people with intense physical activity, intensive exercise with weights, long-distance runners (Marathons).
- •Substance use or abuse (cocaine, heroin, amphetamines).
- •History of hospitalization in Intensive Care Unit
- •History of serious injury
- •Considerable body weight alterations during the previous year (increase or decrease)
- •History of Bariatric surgery
- •Any dietary restriction due to disease (sprue), choice (vegan), or eating disorder (anorexia nervosa).
结局指标
主要结局
Appendicular skeletal muscle mass reference measurements of healthy young adults in Greece
时间窗: 01/06/2022
Measurements of appendicular skeletal muscle mass of healthy young adults in Greece that will be used to define sarcopenia in older adults and as normative values.
Define reference measurements for muscle performance
时间窗: 01/06/2022
Reference measurements for walking speed
Define reference measurements for muscle strength.
时间窗: 01/06/2022
Reference measurements for hand grip
次要结局
- Correlations between the different tools used to measure muscle mass(01/06/2022)
- Correlation of muscle mass with demographic characteristics(01/06/2022)
- Correlation of bone mass with demographic characteristics(01/06/2022)
- Correlation of adherence to Mediterranean diet with muscle mass(01/06/2022)
- Correlation of fat mass with demographic characteristics(01/06/2022)