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临床试验/NCT02858115
NCT02858115已完成不适用

Use of Mini-fluid Challenge for Fluid Responsiveness Prediction During One-lung Ventilation

Assistance Publique Hopitaux De Marseille1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2014年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
50
试验地点
1
主要终点
Velocity time index

研究概览

简要总结

During thoracic surgery, an excessive use of fluid results in pulmonary complications. Dynamic fluid responsiveness predictors are not easily usable during one lung ventilation. The investigators hypothesized that the assessment by transesophageal echocardiography (TEE) of subaortic velocity time index (VTI) variation after 100 ml of crystalloid would predict fluid responsiveness in patients receiving one-lung ventilation.

This retrospective, observational, single center study was from January 2014 to December 2015. The investigators included 105 patients requiring one lung ventilation lung resection. The investigators analysed 39 patients presenting an acute circulatory failure. 100 ml of crystalloid was infused over 1-min. After an echocardiographic assessment at 1-min, remaining 400 ml were administered over 14-min Fluid responsiveness was defined as an increase in the VTI above 15% after infusion of 500 ml of crystalloid.

研究设计

研究类型
Observational
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Lung resection
  • Acute circulatory failure
  • One-lung ventilation

排除标准

  • Sinusal rhythm

结局指标

主要结局

Velocity time index

时间窗: one day

: Echographic assesment of cardiac output

Fluid responsiveness

时间窗: one day

increase of cardiac output of more than 15%

次要结局

  • Pulsed pressure variation(one day)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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