A randomized controlled trial of the effectiveness of Transcranial Direct Current Stimulation (tDCS) for Treatment of Major Depression

All India Institute of Medical Sciences New Delhi0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年6月26日

试验速览

暂无简介。

•1.Between age 18-55 years
•2.Either gender
•3.Right-handed individuals
•4.Patients fulfilling the Diagnostic and Statistical Manual of Mental Disorders version 5 (DSM 5) criteria for the diagnosis of MDD
•5.Ability to read Hindi or English language
•6.Willing to give informed consent
•7.Medication naÃ¯ve or Treatment free from prior 2 weeks or on a stable standard antidepressant regimen {including selective serotonin reuptake inhibitors (SSRIs), serotonin-noradrenaline reuptake inhibitors (SNRIs), monoamine oxidase inhibitors (MOAIs) or tricyclic (TCAs)} with no change in treatment 4-weeks prior to tDCS intervention
•8.HAMD score >= 24 (severe depression)(Chistyakov et al., 2010; Goodman et al., 2006)

•1.Chronic medical or neurological illness (previously diagnosed)
•2.Lifetime substance use disorder (excluding tobacco or caffeine) (as per DSM-5)
•3.Suffering from or any psychiatric illness other than MDD
•4.Not cooperative for testing
•5.Past history of significant head injury
•6.Known case of intellectual disability
•7.Known or suspected pregnancy or currently lactating
•8.Head metal implants
•9.Subjects with significant suicidal risk upon clinical assessment
•10.Any history of seizure
•11.Previous history of receiving any brain surgical procedures
•12.Implanted metal in their body
•13.Electrical or magnetic stimulation on brain in the previous three months

发起方

All India Institute of Medical Sciences New Delhi