跳至主要内容
临床试验/NL-OMON56353
NL-OMON56353招募中不适用

Beta-Alanine Supplementation in patients with COPD following an exercise training program to strengthen the lower limbs. - BASE-ELECTRIC

CIRO0 个研究点目标入组 68 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
68

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • - COPD, GOLD group B or D (high symptomatic)
  • - Grade 3 or higher on the Modified Medical Research Council (mMRC) dyspnoea
  • - Clinically stable according to the pulmonary physician, i.e. no exacerbation
  • and/or hospitalization within the previous 4 weeks.
  • - Age between 40-80 years
  • - Cycle endurance time, measured during a constant work rate test (CWRT) at 75%
  • of the peak cycling load, is 100-300 seconds and/or Quadriceps Muscle Strength
  • (peak torque), measured with a computerized dynamometer, is less than 80% of
  • the predicted value
  • - Attending the regular inpatient pulmonary rehabilitation program in CIRO and
  • receiving NMES as the primary muscle training modality.
  • - No use of anabolic steroids during the inpatient pulmonary rehabilitation
  • program in CIRO

排除标准

  • - Instable cardiac disease
  • - Neurological disease and/or musculoskeletal disease that preclude safe
  • participation in an exercise test
  • - History of drugs/alcohol abuse in the past 10 years
  • - Vegetarianism
  • - Inability to understand the Dutch language
  • - Self-reported β-alanine supplementation in the past 3 months
  • - Participation in pulmonary rehabilitation within the past 12 months

研究者

发起方
CIRO

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