NL-OMON49542招募中3 期
Pentoxifylline dose optimization in preterm neonatal sepsis - Pentoxifylline in neonatal sepsis
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 2 至 11（—）
入选标准
- •- Neonates with gestational age <30 weeks
- •- suspected of late onset sepsis with blood drawn for blood culture and
- •inflammatory biomarkers
- •- IL-6 > 500 pg/ml and/or CRP > 50 mg/L
排除标准
- •- PTX therapy cannot be started within 24 hours of start of antibiotic
- •- Patients with known major congenital defects (e.g. congenital heart disease,
- •pulmonary, or gastrointestinal anomalies) will also be excluded.
- •- If subjects have IL-6 values exceeding 25000 pg/mL at time of onset they will
- •also be excluded. High IL-6 values represent severe episodes of sepsis and high
- •IL-6 values are associated with high mortality rates.
- •- Patients who already participated in this trial during an earlier episode of
- •late onset sepsis.
- •- Patients with pH below 7 in two consecutive blood samples, with at least 1
- •hour between the blood samples, at start of sepsis episode.
研究者
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