Health Effects of Reducing Sedentary Behavior
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 2
- 主要终点
- Daily steps
研究概览
简要总结
A recent review indicated that sedentary behavior has been associated with increased morbidity and mortality but the intervention studies frequently focus only on changing sedentary behavior (reducing sedentary time) without measuring health-associated outcomes. Elevated cortisol (related to stress) has been linked with health risks. Improved physical fitness has been linked with improved cortisol responses to psychosocial stressors. In addition, increased physical activity induced favorable effects upon low density lipoprotein, high density lipoprotein, and total cholesterol. Previous study also indicated that increasing daily steps have positive effect on blood glucose in people with impaired glucose tolerance. Ultimately, the investigators think that sedentary intervention and stress management may have benefits on these health indicators. As such the investigators will examine whether sedentary intervention or stress management can have positive effect on human health by measuring salivary cortisol, blood lipid profile, fasting blood glucose, blood pressure, resting energy expenditure, and body composition.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age: 18-65 years.
排除标准
- •Unable/unwilling to provide informed consent.
- •Having mobility impairment.
- •Current severe untreated depression (i.e., score in the severe depression range on the Hospital Anxiety and Depression Scale; HADS).
- •Women who are pregnant or nursing.
- •Currently smoking (within last 12 months).
- •Currently use medications that affect salivary cortisol level (i.e. prednisone, dexamethasone).
- •Have been diagnosed Addison's disease.
研究组 & 干预措施
Control group (C)
干预措施: Control (Behavioral)
Sedentary behavior group (SB)
干预措施: Reducing sedentary behavior (Behavioral)
Stress management group (SR)
干预措施: Reducing stress (Behavioral)
结局指标
主要结局
Daily steps
时间窗: Baseline (pre-intervention) and 4 weeks (post-intervention)
Changes in daily steps measured via pedometer.
Stress improvement in sedentary behavior group (SB)
时间窗: Baseline (pre-intervention) and 4 weeks (post-intervention)
Improvement in stress as measured via Perceived Stress Scale (PSS) in SB.
Stress improvement in stress management group (SR)
时间窗: Baseline (pre-intervention) and 4 weeks (post-intervention)
Improvement in stress as measured via Perceived Stress Scale (PSS) in SR.
Compare the changes of stress levels between SB and SR
时间窗: Baseline (pre-intervention) and 4 weeks (post-intervention)
Compare the changes of stress levels as measured via Perceived Stress Scale (PSS) between SB and SR.
次要结局
- Changes in high density lipoprotein (HDL) in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in low density lipoprotein (LDL) in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in blood pressure in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Compared the changes in TG between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in body fat in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in fasting blood glucose in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Compared the changes in TC between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in triglyceride (TG) in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in weight in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in high density lipoprotein (HDL) in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Compared the changes in LDL between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Compared the changes in fasting blood glucose between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Compared the changes in blood pressure between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Change in resting energy expenditure in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in body fat in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in total cholesterol (TC) in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in blood pressure in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in triglyceride (TG) in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in fasting blood glucose in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Compared the changes in weight between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Change in resting energy expenditure in SB(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in low density lipoprotein (LDL) in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in total cholesterol (TC) in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Changes in weight in SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Compared the changes in HDL between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
- Compared the changes in body fat between SB and SR(Baseline (pre-intervention) and 4 weeks (post-intervention))
研究者
Martin Binks
Associate Professor
Texas Tech University