Effects of Dietary Protein Intake From Beef/Pork and Soy/Legumes on Appetite, Mood, and Weight Loss
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 37
- 试验地点
- 3
- 主要终点
- Increasing protein intake from lean beef/pork or soy/legumes sources will result in progressively decreased daily composite hunger and desire to eat, and increased fullness. The responses will not be different between groups of subjects.
研究概览
简要总结
The primary aims of this study are to assess the effects of habitual dietary protein intakes across the acceptable macronutrient distribution range with lean beef/pork or soy/legumes as the predominate sources of protein on indices of daily appetite and mood, and on postprandial appetite, mood, energy expenditure, and glycemic responses during energy-restricted weight loss in overweight adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age range: 21 years and older
- •Body mass index between 27.0-36.9 kg/m2
- •Non-smoking (within the last 6 months)
- •Weight stable (< 3 kg (~7 lbs) weight gain or loss within last 3 months)
- •Energy need for weight maintenance 1950-2750 kcal/day
- •Not dietary restrained
- •Menstruating women not pregnant or lactating
- •Constant habitual activity patterns (within last 3 months)
- •No Acute Illness (or have chronic diseases known to influence protein or energy metabolism)
- •Non-diabetic
- •Clinically normal blood profiles (within 10% of clinical normalcy)
- •Non-hypertensive
- •Not taking medications known to influence appetite or metabolism
- •Willingness to eat study foods
- •Able to travel to testing facility
排除标准
- •Age: <21 years
- •Body mass index: outside of the 27.0-36.9 kg/m2 range
- •Smoker (currently or within the last 6 months)
- •Gained or lost > 3.0 kg (7 lbs) within the last 3 months
- •Energy need for weight maintenance < 1950 or > 2750 kcal/day
- •Dietary restrained (≥ 14 on Three Factor Eating Questionnaire)
- •Pregnant, lactating, or non-menstruating women
- •Clinically diagnosed as a diabetic, or with liver or kidney disease/dysfunction, or osteoporosis
- •Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
- •Hypertensive
- •Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
- •Allergies to eggs
- •Lactose intolerance
- •Unwillingness to eat study foods
- •Inability to travel to testing facility
研究组 & 干预措施
Arm 1: Beef/Pork
Participants consuming diet with beef/pork as predominate sources of protein
干预措施: Beef/Pork (Other)
Arm 2: Soy/Legumes
Participants consuming diet with soy/legumes as predominate sources of protein
干预措施: Soy/Legumes (Other)
结局指标
主要结局
Increasing protein intake from lean beef/pork or soy/legumes sources will result in progressively decreased daily composite hunger and desire to eat, and increased fullness. The responses will not be different between groups of subjects.
时间窗: 14 weeks
次要结局
- Increasing the protein content of a test will result in progressively more robust and sustained changes in postprandial appetite and energy expenditure and blunted glycemic response. The responses will not be different between the groups of participants.(14 weeks)
研究者
Wayne Campbell
Wayne Campbell, Ph.D.
Purdue University