Relationship Between the Sarcopenia Diagnostic Cut-points and Functionality in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- First criteria of sarcopenia diagnostic: elbow flexion strength
研究概览
简要总结
This is a cross-sectional study conducted in older adults living in Valencia Province in order to establish the cut-off points of the multicriteria diagnostic of sarcopenia through functionality and frailty variables.
详细描述
Sarcopenia is a geriatric syndrome that involves a gradual and generalized loss of the mass and strength of the skeletal muscles. Currently, there is an international debate about the criteria and reference values for the sarcopenia diagnosis, and the main scientific societies encourage improving research on this. The biggest problem lies in the assessment of the diagnostic criterion of muscle mass while the criterion of muscular strength seems safer and more robust. Experts point out the need to adjust the muscle mass indexes to the characteristics of the population studied, and the convenience of relating the three diagnostic criteria of sarcopenia (muscle mass and strength, and walking speed) with other variables that report about functionality and frailty in older adults.
The main objective is to establish different cut-off points for the diagnostic criteria of sarcopenia and relate them with other instruments for assessing functionality in older population of Valencia Province.
To this purpose, data will be collected through various tests and questionnaires about: clinical, demographic and anthropometric characteristics; muscle mass; muscle strength; walk speed; physical and cognitive function; nutritional status; self-perception of health; comorbidity and frailty. With this information it will be possible, as primary outcome, to determine a more sensitive, reliable and valid muscle mass index to predict sarcopenia, and, as a secondary outcome, to establish the relationship between the multicriteria diagnostic of sarcopenia with the functional and frailty variables.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •People aged > 65 years
- •Residents in Valencia Province (Living-Community, Day-Centers and institutionalized)
排除标准
- •Lobo Mini-exam cognoscitive < 18 score
- •Any disorder that prevents from performing the assessment tests.
- •Recent hospitalization or who are in a acute process of any illness (less one month).
结局指标
主要结局
First criteria of sarcopenia diagnostic: elbow flexion strength
时间窗: The cohort group will be assessed in one day visit.
Muscle strength measured by the isometric elbow flexion (reference: Phys Ther. 1996;76(3):248-59).
Third criteria of sarcopenia diagnostic: walk speed
时间窗: The cohort group will be assessed in one day visit.
Walk speed measured by the Short Physical Performance Balance test (SPPB) (reference: J Gerontol A Biol Sci Med Sc 2000; 55(4):M221-31.
First criteria of sarcopenia diagnostic: knew extension strength
时间窗: The cohort group will be assessed in one day visit.
Muscle strength measured by the isometric knew extension (reference: Phys Ther. 1996;76(3):248-59).
First criteria of sarcopenia diagnostic: hand grip strength
时间窗: The cohort group will be assessed in one day visit.
Muscle strength measured by the isometric hand grip strength (reference: Age and Aging. 2010;39:412-23).
Second criteria of sarcopenia diagnostic: muscle mass
时间窗: The cohort group will be assessed in one day visit.
Muscle mass estimated by Bioimpedance analysis (BIA) (reference: J Aging Phys Act. 2015;23(4):597-606).
次要结局
- Functionality: Modified Baecke Questionnaire(The cohort group will be assessed in one day visit.)
- Comorbidity(The cohort group will be assessed in one day visit.)
- Functionality: Barthel Index(The cohort group will be assessed in one day visit.)
- Frailty: Fried Scale(The cohort group will be assessed in one day visit.)
- Functionality: Lawton and Brody Questionnaire(The cohort group will be assessed in one day visit.)
- Frailty:Frail Scale(The cohort group will be assessed in one day visit.)
- Frailty: Kihon Check List (KCL)(The cohort group will be assessed in one day visit.)
研究者
Maria dels Angels Cebria i Iranzo, PT, PhD
Assistant professor
University of Valencia
