NCT00354588已完成不适用
Observational Study on the Prognostic Significance (Renal and Cardiovascular) of Arterial Stiffness and Arterial Wave Reflections in Patients With Mild to Moderate Renal Impairment
Klinikum Wels-Grieskirchen1 个研究点 分布在 1 个国家目标入组 115 人开始时间: 2006年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 115
- 试验地点
- 1
- 主要终点
- renal endpoint
研究概览
简要总结
- Cardiovascular risk is high in patients with renal failure.
- Cross-sectional studies have indicated a relationship between arterial stiffness and renal function. However, there are no prospective longitudinal studies in the literature.
- In dialysis patients, arterial stiffness as well as wave reflections, predict mortality. However, there are no data on patients with mild-to-moderate renal impairment available.
- Therefore, we designed a study to test the hypothesis that: a) measures of arterial stiffness and wave reflections predict the progression of renal impairment in patients with mild-to-moderate renal failure; and b) measures of arterial stiffness and wave reflections predict cardiovascular events in patients with mild-to-moderate renal failure
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •chronic renal failure patients (KDOQI III, IV) undergoing regular control visits at our nephrology department
- •> 19 years
- •written informed consent
排除标准
- •atrial fibrillation
- •valvular heart disease
- •severely impaired systolic function
- •no informed consent
结局指标
主要结局
renal endpoint
doubling serum creatinine, need for dialysis, renal transplantation
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
4 期
Renal and Systemic Vascular Resistance in Chronic Kidney Disease (CKD)Chronic Kidney InsufficiencyVasodilationHypertensionNCT01380717University of Aarhus83
已完成
不适用
Prognosis of Patients With Acute Coronary Syndrome Complicated With Renal Insufficiency(PACS-RI)Acute Coronary SyndromeNCT03044990Henan Institute of Cardiovascular Epidemiology2,014
撤回
不适用
Renal Function in Adults With Congenital Heart Disease.Cardiovascular AbnormalitiesKidney FailureNCT00807274Royal Brompton & Harefield NHS Foundation Trust1,200
已完成
不适用
REnal reCOVery After ECMO for Cardiogenic Shock (RECOVECMO)Renal Replacement TherapyVenoarterial Extracorporeal Membrane OxygenationCardiogenic ShockNCT05788211University Hospital, Bordeaux93
已完成
不适用
Identification of Cardiovascular Risk Factors Linked to Renal Failure ProgressionChronic Renal FailureNCT00608998University Hospital, Montpellier120