The Effect of Epidural Steroid Injections on Glycemic Control in Diabetic Patients According to the Doses of Steroids
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 125
- 试验地点
- 2
- 主要终点
- fasting blood glucose level
研究概览
简要总结
There has been no reports of the effect of various kinds of steroid or various dose of steroid which are commonly used in the clinical setting. Previous studies have simply shown that the blood glucose level is elevated in diabetes patients and did not show or suggest the adequate strategy of epidural steroid injection in diabetes patients regarding steroid type, dosage or injection interval. Therefore, the investigators tried to evaluate the effect of different dosage of triamcinolone, which is a commonly used steroid in epidural steroid injection, on the blood glucose level.
详细描述
It is well known that blood glucose level is elevated in diabetes patients more than non-diabetes patients who underwent the epidural steroid injection. However, there has been no reports of the effect of various kinds of steroid or various dose of steroid which are commonly used in the clinical setting. Previous studies have simply shown that the blood glucose level is elevated in diabetes patients and did not show or suggest the adequate strategy of epidural steroid injection in diabetes patients regarding steroid type, dosage or injection interval. Therefore, the investigators tried to evaluate the effect of different dosage of triamcinolone, which is a commonly used steroid in epidural steroid injection, on the blood glucose level.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •subjects who undergo epidural steroid injection (caudal epidural injection or selective transforaminal block) in the pain medicine outpatient clinic
- •subjects older than 20 yrs.
排除标准
- •ASA (American society of Anesthesiologists class) III or more
- •severe cardiopulmonary disease or brain disorder
- •Subjects diagnosed uncontrolled diabetes with complications
- •subjects undergoing hormone therapy
- •subjects with active infection
- •subjects with pregnancy
- •subjects with recent stress condition such as surgery or trauma
- •subjects with active neurologic disorder
- •those with anticoagulation therapy
结局指标
主要结局
fasting blood glucose level
时间窗: at 7:00 am of postprocedure day 7
fasting blood glucose
时间窗: at 7:00 am of postprocedure day 14
次要结局
- post-prandial glucose level(2 hour after dinner at postprandial day 1, 2, 3, 4, 5, 6, 7, 14)
- visual analogue scale of subjective pain(at 7 p.m. of postprocedure day 1, 2, 3, 4, 5, 6, 7, 14)
研究者
Woo Seog Sim
Associate Professor
Samsung Medical Center