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临床试验/NCT04152044
NCT04152044Unknown不适用

Elucidating the Role of Obesity, Liver Function and Pathology With Overall Outcomes in Oesophageal Cancer

St. James's Hospital, Ireland1 个研究点 分布在 1 个国家目标入组 658 人开始时间: 2019年11月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
658
试验地点
1
主要终点
Overall Survival

研究概览

简要总结

There is an established link between sarcopenia and outcomes in oesophageal cancer. There is scant reports in the literature regarding the influences of different obesity in different compartments.

详细描述

Oesophageal cancer rates are increasing as a result of obesity in Western society. Thr investigators are evaluating the influence of viscerala dn subcutaneous obesity on overall outcomes of the participants. In addition the investigators are evaluating if there is a correlation with Liver Function Tests and liver histopathology such as steatosis on survival in participants and post operative sequele.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Those undergoing oesophagectomy

排除标准

  • patients who only had chemotherapy/chemoradiotherapy without surgery

结局指标

主要结局

Overall Survival

时间窗: 1 year

Disease free survival

时间窗: 1 year

次要结局

未报告次要终点

研究者

发起方
St. James's Hospital, Ireland
申办方类型
Other
责任方
Principal Investigator
主要研究者

Noel Edward Donlon

Principal Investigator

St. James's Hospital, Ireland

研究点 (1)

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