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临床试验/NCT05788471
NCT05788471尚未招募不适用

Effect of Neurodynamic Mobilization on Median Nerve Conduction Velocity in Carpal Tunnel Syndrome

Cairo University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2023年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
40
试验地点
1
主要终点
Assessing the change in nerve conduction velocity of the median nerve.

研究概览

简要总结

The purpose of this study is to examine:

  1. The effect of neurodynamic mobilization on the sensory and motor median nerve conduction velocity in carpal tunnel syndrome.
  2. The effect of neurodynamic mobilization on the wrist pain in carpal tunnel syndrome.
  3. The effect of neurodynamic mobilization on the hand function in carpal tunnel syndrome.

详细描述

The findings of this study will provide physiotherapists with information to know if neurodynamic mobilization techniques is effective on median nerve conduction velocity in carpal tunnel syndrome also this will improve our body of knowledge about the best modalities for treating carpal tunnel syndrome. The finding of this study may help carpal tunnel syndrome patients to avoid the exposing to complications as a result of compression of median nerve in carpal tunnel syndrome.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
20 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Forty carpal tunnel syndrome patients.
  • All participants referred from a physician.
  • Their ages range from 20-50 years old.
  • Both genders will participate in the study.
  • Their BMI ranges between 18.5-24.9kg/m
  • All participants have carpal tunnel syndrome at least in one hand.
  • All participants suffering from mild to moderate carpal tunnel syndrome.

排除标准

  • Previous or current disease or trauma that might affect one or both upper limbs.
  • Metabolic diseases that might associated with entrapment neuropathy such as diabetes mellitus, thyroid diseases, and autoimmune diseases.
  • Pregnant women.
  • Participants with congenital hand deformities.
  • History of hand surgery.
  • Sever cases of carpal tunnel syndrome that suffering from weakness of hand grip and atrophy of thenar muscle.

结局指标

主要结局

Assessing the change in nerve conduction velocity of the median nerve.

时间窗: at baseline and after 4 weeks of intervention

By using Electromyography apparatus measuring nerve conduction velocity of the median nerve. (motor and sensory in m/s)

Assessing the change in wrist joint pain

时间窗: at baseline and after 4 weeks of intervention

By using Pressure pain threshold (PPT) is defined as the minimal amount of pressure that produces pain. A simple handheld pressure algometer (PA) with a spring is commonly used, although more sophisticated electrical devices with a strain or pneumatic pressure gauge have been developed. They hold the peak force or pressure (kp (kilopond) = 10 N, Newton = 100 kPa (kilopascal)) until tared, and some may also be connected to a computer and thus have continuous output. PPT measured with a probe 1.6 mm in diameter or larger reflects the tenderness of deep tissues as anesthesia of skin only affects the results of smaller probes.

Assessing the change in functional activity of the hand

时间窗: at baseline and after 4 weeks of intervention

By using Modified DASH questionnaire will be used for functional activity of the hand. The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire is a 30-item questionnaire that looks at the ability of a patient to perform certain upper extremity activities. This questionnaire is a self-report questionnaire that patients can rate difficulty and interference with daily life on a 5 point Likert scale. The QuickDASH tool uses a 5-point Likert scale from which the patient can select an appropriate number corresponding to his/her severity/function level.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Raghda Ahmed Mohammed Ebrahim

Principal Investigator

Cairo University

研究点 (1)

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