ISRCTN25839413进行中（未招募）Unknown
Alterations in small non-coding RNAs (miRNAs) and the potential role in the development of aseptic loosening after total hip replacement: Study protocol for a retrospective, observational, cross-sectional study
niversity of Patras0 个研究点目标入组 51 人开始时间: 2024年3月18日最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 51
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. Aged >40 years old
- •2. Patients undergoing primary total hip arthroplasty (THA) due to degenerative hip osteoarthritis (Group A)
- •3. Patients who underwent primary THA, without clinical and radiological evidence of periprosthetic osteolysis and aseptic loosening (Group B)
- •4. Patients undergoing revision surgery after primary THA, with clinical and radiological evidence of periprosthetic osteolysis and aseptic loosening (Group C)
排除标准
- •1. Revision total hip arthroplasty (THA) surgery
- •2. Bilateral THA or hemiarthroplasty on the contra-lateral hip
- •3. Pre-existing other joint replacement
- •4. Inflammatory markers and intraoperative cultures indicating potential septic loosening
- •5. Cancer or immunodeficiency, patients receiving chemotherapy or immunosuppressive medication
- •6. Autoimmune diseases
- •7. Severe cognitive defects or psychiatric disorders
- •8. Inability to provide written informed consent to the study
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