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临床试验/NCT05903677
NCT05903677尚未招募不适用

The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery

Assiut University0 个研究点目标入组 50 人开始时间: 2023年7月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
50
主要终点
Post cardiac surgery AKI according to KDIGO criteria with low preoperative magnesium level

研究概览

简要总结

Detection the relationship between preoperative ionized magnesium levels and the risk of acute kidney injury after cardiac surgery.

详细描述

Acute kidney injury (AKI) is a major medical problem that is of particular concern after cardiac surgery. The reported prevalence of cardiac surgery-associated acute kidney injury (CSA-AKI) is up to 30% and is independently associated with an increase of morbidity and mortality .So this study is for measuring preoperative ionized magnesium levels of patients who will undergo cardiac surgeries then measuring postoperative serum creatinine, BUN and urine output to detect if they developed AKI or not and if there is a relationship between the post cardiac surgery AKI and preoperative ionized magnesium levels.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients more than or equal 18 yrs.
  • patients undergoing cardiac surgery between July 2023 and July 2024

排除标准

  • patients with known Kidney disease.
  • patients less than 18 yrs

结局指标

主要结局

Post cardiac surgery AKI according to KDIGO criteria with low preoperative magnesium level

时间窗: Baseline

Measuring preoperative magnesium level and postoperative kidney functions in form of serum creatinine in umol/L , BUN in mmol/L and urine output ml/h to detect the relationship between preoperative low magnesium level and risk of acute kidney injury after cardiac surgery.

Post cardiac surgery AKI according to KDIGO criteria with normal or high preoperative magnesium level

时间窗: basline

Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery.

Post cardiac surgery normal kidney functions with low preoperative magnesium level

时间窗: basline

Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mostafa Ahmed Kaleed Abdelhalim

Resident doctor

Assiut University

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