Impact du Bilan et de la Prise en Charge Des comorbidités en médecine Interne Sur le Risque Cardiovasculaire
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Screening and management of comorbidities effect on cardiovascular risk factors
研究概览
简要总结
The aim of assessing and managing cardiovascular risk is to avoid, limit or delay cardiovascular morbidity and mortality. Planned internal medicine hospitalization is developed around the management of cardiovascular risk in patients at high cardiovascular risk, whether in primary prevention or secondary prevention.
During planned hospitalization, patients benefit from comprehensive, personalized and adapted care for their comorbidities and their CVRF (cardiovascular risk factors).
This study will make it possible to evaluate this overall course of multidisciplinary management of comorbidities of patients at high cardiovascular risk.
详细描述
The aim of assessing and managing cardiovascular risk is to avoid, limit or delay cardiovascular morbidity and mortality. Planned internal medicine is developed around the management of cardiovascular risk in patients at high cardiovascular risk, whether in primary prevention patients, combining several cardiovascular risk factors CVRF (arterial hypertension, metabolic syndrome, diabetes, dyslipidemia, etc.), or patients in secondary prevention who have several CVRFs and have already had a major cardiovascular event such as ischemic heart disease, heart failure.
During scheduled hospitalization, patients benefit from comprehensive care. Additional examinations include measurement of blood pressure, cardiac ultrasound, vascular Dopplers, usual biological assessment (lipid, glycemic, renal, iron assessment, CRP), and on a case-by-case basis, ventilatory polygraphy to screen for obstructive sleep apnea hypopnea syndrome, pulmonary function tests if the patient is a smoker to screen for chronic obstructive pulmonary disease, coronary function test to screen for ischemic heart disease if indicated. Comorbidities are thus identified and summarized, and patients benefit from personalized and adapted care for their comorbidities and CVRFs.
Cardiovascular risk reduction strategy programs targeting high-risk patients are essential and their evaluation is necessary.This study will make it possible to evaluate this overall course of multidisciplinary management of comorbidities in patients at high cardiovascular risk in internal medicine.
The innovative nature of the project is the possibility to cross-reference the comorbidities and the cardiovascular and metabolic data of these patients at high cardiovascular risk with their evolving risk level over time. This will also make it possible to highlight which markers are the most effective to better stratify cardiovascular risk, or even consider personalized phenotyping. The coexistence of all these parameters within the same database represents a unique opportunity to study their respective influences in a population of patients at high cardiovascular risk.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •High-Risk Cardiovascular patients either receiving:
- •Primary prevention because they have never had a cardiovascular event but have several cardiovascular risk factors such as high blood pressure particularly resistant, metabolic syndrome, diabetes , dyslipidemia, metabolic steatosis
- •Or secondary prevention because they have already had a major cardiovascular event such as ischemic heart disease, heart failure
- •Aged 18 and over
- •Patient benefiting from comorbidities assessment during their planned hospitalization in the internal medicine department.
排除标准
- •Patient refusal
- •Subject not registered in social security system
- •Pregnant or breastfeeding woman
- •Patient unable to give their informed consent, protected adult, vulnerable people
- •Subject deprived of liberty by judicial or administrative decision
结局指标
主要结局
Screening and management of comorbidities effect on cardiovascular risk factors
时间窗: 3 months after enrollment
Effect of comorbidities screening and management on cardiovascular risk factors in patients at high-risk of a cardiovascular event. The life's simple 7 score will be used at enrollment and 3 months afterward. The score includes four modifiable behaviors (smoking, weight, healthy/unhealthy eating diet and physical activity) and three biometric measures (blood pressure, cholesterol and blood sugar level). These seven factors are classified into three categories: ideal, intermediate and poor. Life's Simple 7 summary score ranges from 0 to a maximum of 14 points, with a higher score indicating healthier status.
次要结局
- C-reactive protein levels(At enrollment)
- Screening and management of comorbidities effect on the balance of cholesterol(3 and 12 months after enrollment)
- Screening and management of comorbidities effect on tobacco consumption(3 and 12 months after enrollment)
- Screening and management of comorbidities effect on A1C level(3 and 12 months after enrollment)
- Screening and management of comorbidities effect on patient's weight(3 and 12 months after enrollment)
- Screening and management of comorbidities effect on the balance of blood sugar level(3 and 12 months after enrollment)
- Screening and management of comorbidities effect on cardiovascular risk factors(12 months after enrollment)
- Screening and management of comorbidities effect on blood pressure(3 and 12 months after enrollment)
- Cardivascular events incidence(12 months after enrollment)
- Initial participant's comorbidities(At enrollment)
- Lipoprotein a levels(At enrollment)