Influence of Sugammadex on Facial Nerve Monitoring in Parotid Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- evoked EMG amplitude of facial nerve
研究概览
简要总结
To investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery
详细描述
Intraoperative neuromonitoring (IONM) of facial nerve has been applied in identifying and preserving facial nerve during parotid surgery. In this setting, even a single dose of nondepolarizing muscle relaxant may lead to delayed and weakened electromyography (EMG) signal in facial nerve monitoring during parotid surgery. The aim of this study was to investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •undergoing parotid surgery
排除标准
- •facial nerve injury, renal failure, liver cirrhosis, neuromuscular disease
研究组 & 干预措施
Sugammadex group
received single dose of rocuronium for anesthesia and sugammadex at skin incision
干预措施: sugammadex (Bridion) (Drug)
结局指标
主要结局
evoked EMG amplitude of facial nerve
时间窗: up to first post-op day
次要结局
未报告次要终点
研究者
I-Cheng Lu
Visiting staff
Kaohsiung Medical University Chung-Ho Memorial Hospital