Fluid Balance During Exercise in the Heat With Water, Flavored Placebo, or a Carbohydrate-electrolyte Beverage Intake (The APEX Study)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Fluid Balance
研究概览
简要总结
The purpose of the APEX study is to determine whether carbohydrate-electrolyte beverage intake promotes fluid balance during exercise in the heat compared with water or placebo intake.
详细描述
Exercise in the heat has large effects on cardiovascular strain, the ability to regulate core body temperature, and performance because of an increase in the reliance on body fluid distribution to the skin to maintain adequate sweat rates and heat dissipation. Carbohydrate-electrolyte beverage intake during exercise in the heat may improve fluid balance and subsequent physical performance.
The participants will be assigned each arm in a randomized, counterbalanced, cross-over fashion separated by at least 2 weeks. Participants will be placed in a heated environment for the duration of the exercise intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Males aged 18-35 years
- •Healthy (No uncontrolled disease)
排除标准
- •No medications that influence fluid balance
- •No uncontrolled disease
结局指标
主要结局
Fluid Balance
时间窗: 120 minutes
Fluid balance will be determined by change in body weight during the 120 minutes steady-state exercise bout in the heat.
次要结局
- Physical Performance(30 minutes)
- Rate of fluid uptake in the GI tract(30 minutes)
- Amount of carbohydrate oxidized(120 minutes)
- Cardiovascular responses(120 minutes)
- Thermoregulatory responses(120 minutes)