Comparison Between Interleukin 6 and Procalcitonin in Detecting Sepsis and Incidence of Mortality in Burn ICU Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Occurrence of sepsis and septic shock
研究概览
简要总结
The investigators will compare the efficacy of Interleukin-6 (IL-6) as a better indicator than procalcitonin in burn patients with sepsis or septic shock regarding success of treatment and early ICU discharge.
详细描述
Interleukin 6 and procalcitonin will be sampled for all patients on days 1, 3, 7, and 10.
Treatment plan will be initiated to all patients according to the burn ICU protocol.
According to the lab results, interleukin 6 and procalcitonin will guide the investigators to take decisions regarding clinical improvement and ICU stay.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with acute burn admitted to burn ICU within 24 hours from the burn incidence.
- •patients with burn percentage of 25% to 50% of total body surface area
- •patients with second to third degree burns
- •ASA 1 and ASA 2 patients
排除标准
- •Burn percentage more than 50% or less than 25% of total body surface area
- •Having autoimmune diseases
- •Cancer patients
- •ASA 3 and ASA 4 patients
研究组 & 干预措施
Burn ICU patients
Interleukin 6 and procalcitonin will be sampled for all patients on days 1, 3, 7, and 10. Treatment plan will be initiated to all patients according to the burn ICU protocol.
干预措施: Interleukin 6 (Diagnostic Test)
结局指标
主要结局
Occurrence of sepsis and septic shock
时间窗: From day 1 to day 10 in burn ICU
Prediction of occurrence of sepsis and septic shock
次要结局
- Length of ICU stay(One month after ICU admission)