A Registry on Outcomes in Women Undergoing Assisted Reproductive Techniques After Recurrent Failures
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 624
- 试验地点
- 1
- 主要终点
- Number of live births
研究概览
简要总结
Assisted Reproductive Technologies (ARTs) are widely used in couples with fertility problems. However, despite ART treatment options have evolved over time, the implantation rate remains rather low.
A possible role for inherited and acquired thrombophilias has been invoked, especially in women with previous implantation failures. However, several factors could play a role in these conditions.
A potential benefit of low-molecular-weight heparin (LMWH) in improving ART outcomes, independently of the presence of thrombophilia, has been recently suggested.
This register is designed in order to better define all possible variables influencing ART outcome and improve clinical management of women with previous implantation failures. During this study the investigators will collect and evaluate clinical data regarding the first cycle in women with previous ART failures.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •2 or more implantation failures/losses of clinical pregnancies after ART
- •ART cycle at enrolment
- •Informed consent
排除标准
- •Ovarian hypofunction
- •Uterine pathology
- •Hydrosalpinges
- •Previous inclusion in the study
结局指标
主要结局
Number of live births
时间窗: 10 months
次要结局
- Number of clinical pregnancies after ART(10 months)
研究者
Elvira Grandone, MD, Head of Unit
Head of Unit
Casa Sollievo della Sofferenza IRCCS