Re-engagement at Discharge 2: Improving Post-hospital Outcomes for Adults With HIV in Zambia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 97
- 试验地点
- 2
- 主要终点
- Post-Discharge Clinic Visits
研究概览
简要总结
Early post-discharge mortality is high among Zambians living with HIV admitted to the hospital. This may be due to missed opportunities in post-discharge care, such as inadequate follow-up and treatment. In this study the investigators will develop and pilot a new approach to post-discharge HIV care to improve care coordination and treatment adherence.
详细描述
Many people living with HIV (PLHIV) have poor outcomes following hospitalization, including high mortality, readmission, and gaps in HIV care engagement. This is likely multi-factorial and not all etiologies may be modifiable. While high mortality may due to incurable cancer, the majority of deaths in PLHIV are thought to be caused by infectious diseases for which treatments exist. However, succumbing to these life-threatening infections after discharge may be due to poor understanding of discharge instructions, lack of post hospital care, and poor understanding of required follow up. Psychosocial support also plays a role in the mental and physical health of these sick patients.
In ReCharge 1, the investigators gathered formative data and identified at least three major factors that undermine HIV clinical outcomes after hospital discharge. First, there are gaps in continuity of care between the discharging facility and outpatient. Second, support from family is often suboptimal due to lack of understanding on the cause of illness, lack of HIV status disclosure, and the cost of care. Third, HIV comorbidities may underpin or complicate the immediate reason for discharge or the post-discharge engagement in care. These data were disseminated to local experts in Zambia including from the Ministry of Health and used to create a new care model for post-discharge HIV care. The care model draws from other successful programs in Zambia. In ReCharge 2 the investigators now propose to pilot the program and assess feasibility, acceptability, and potential for clinical impact.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18+ years
- •HIV-positive
- •Hospitalized for at least 1 night at study site
- •Clinically stable and expected to be discharged according to their clinician
- •Objective evidence of suboptimal HIV outcome, defined as HIV viral load above the lower limit of the assay or T-cell cluster of differentiation 4 count <=200.
排除标准
- •Unable to provide informed consent
- •Planning to reside outside of Lusaka urban district after discharge
结局指标
主要结局
Post-Discharge Clinic Visits
时间窗: Through three months post-discharge
Proportion of initial post-discharge visits to the HIV clinic that are attended by the participant's community health worker
Comprehensive Post-Discharge Visits
时间窗: Through three months post-discharge
Number of participants that receive a comprehensive discharge follow-up visit from a community health worker
Post-Discharge Visits
时间窗: Through three months post-discharge
Proportion of discharged patients who are successfully visited after discharge.
Comprehensive Post-Discharge Visits
时间窗: Through three months post-discharge
Number of participants that receive a comprehensive discharge follow-up visit from a community health worker
Post-Discharge Clinic Visits
时间窗: Through three months post-discharge
Proportion of initial post-discharge visits to the HIV clinic that are attended by the participant's community health worker
次要结局
- Mortality(6 months post-discharge)
- HIV Viral Load Suppression(6 months post-discharge)
- Retention in HIV Care(6 months post-discharge)
- Antiretroviral Therapy Clinic Visit(1 month post-discharge)
- Mortality(6 months post-discharge)
研究者
Cassidy Claassen
Associate Professor
University of Maryland, Baltimore
