NL-OMON51910已完成不适用
Evaluation of pharmacokinetic and *dynamic characteristics of norepinephrine for the augmentation of arterial blood pressure in healthy volunteers prior to and during general anesthesia - VASOCONTROL-I
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- American Society of Anesthesiologists (ASA) Physical Status I or II
- •- No exclusion criterion is present
- •- Informed, and willing to give written informed consent.
排除标准
- •- Refusal of the volunteer to participate
- •- Pregnancy
- •- Diseases involving the cardiovascular system (hypertension, coronary artery
- •disease, prior acute myocardial infarction, any valvular and/or myocardial
- •disease involving decrease in ejection fraction, arrhythmias, which are either
- •symptomatic or require continuous medication/pacemaker/automatic internal
- •cardioverter defibrillator)
- •- A difference > 15 mmHg in measured systolic or diastolic blood pressure value
- •(SBP, DBP) between the left and right upper arm, as determined by non-invasive
- •cuff oscillometry during the screening visit.
- •- An increased risk of difficult mask ventilation or tracheal intubation, as
- •judged by the anesthesiologist-researcher.
- •- Pulmonary disease
- •- Gastric or endocrinologic diseases
- •- End-stage liver or kidney failure
- •- Use of tricyclic antidepressive medication or MAO inhibitors.
研究者
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