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临床试验/NCT02002494
NCT02002494已完成不适用

Effect of Different Surgical Positions on the Cerebral Venous Drainage: an Ultrasound Study on Healthy Volunteers

University Health Network, Toronto1 个研究点 分布在 1 个国家目标入组 27 人开始时间: 2013年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
27
试验地点
1
主要终点
R IJV and L IJV Flow

研究概览

简要总结

Our hypothesis is that there will be a decrease in internal jugular venous flow in the park bench position when compared to the supine position. There will also be a change in blood flow in the between right and left internal jugular veins in park bench position, particularly there will be a greater reduction of flow on the dependent side. However, the internal jugular venous flow will be the same in both the prone and supine position.

详细描述

The different positions used in neurosurgery (park bench, prone) for better accessibility to the operating field can impact on the cerebral venous drainage due to the effects of internal jugular venous outflow of blood and may increase intracranial pressure. The kinking of the internal jugular vein due to excessive neck flexion and rotation in park bench or flexion in the prone position may lead to kinking or twisting of the vein. This has been hypothesized as the major cause of disturbed venous drainage during surgery and in postoperative patients may lead to neck swelling, brachial plexus injury, macroglossia (swollen tongue), delayed airway obstruction and increases in intracranial pressure.

Optimal brain perfusion is best in the neutral position of the head, but surgery cannot always be performed with this. Thus, we look to measure the internal jugular venous flow at different positions as there have been little studies looking at this important contributing factor.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult healthy volunteers who are above the age of 18
  • American Society of Anesthesiologists classification (ASA) 1
  • Body mass index (BMI) less than and equal to 35

排除标准

  • ASA 2 and above
  • BMI above 35
  • Lack of informed consent
  • Language barrier
  • Medical students and anaesthesia residents going through the department as part of their rotation

结局指标

主要结局

R IJV and L IJV Flow

时间窗: 1 day

Bilateral internal jugular vein (IJV) flow between supine and right park bench position.

Bilateral Internal Jugular Vein (IJV) Doppler Velocity

时间窗: 1 day

Comparisons of bilateral internal jugular vein (IJV) Doppler velocity between supine and right park bench position.

Right and Left IJV Cross Sectional Area

时间窗: 1 day

Twenty-seven volunteers were included in this study. Comparisons of cross sectional area measurements in both IJVs between supine and right park bench

Bilateral Internal Jugular Vein (IJV) Flow

时间窗: 1 day

Comparisons of bilateral internal jugular vein (IJV) flow between supine and prone position. Data presented as mean (SD) .

Internal Jugular Venous (IJV) Cross Sectional Area

时间窗: 1 day

Comparisons of both jugular vein (IJV) of twenty-seven volunteers in supine and prone positions.

Internal Jugular Venous (IJV) Doppler Velocity

时间窗: 1 day

27 volunteers enrolled to measure the Internal Jugular Venous (IJV) in supine and prone positions

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Lashmi Venkatraghavan

Dr.

University Health Network, Toronto

研究点 (1)

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