The Effect of Epidural Steroid Use on Pain Relief in Patients With Continuous Epidural Nerve Block in Postherpetic Neuralgia Patients.
试验速览
- 阶段
- 4 期
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- VAS score
研究概览
简要总结
The efficiency of epidural steroid injection in patients who has postherpetic neuralgia is well known. In this study, the purpose is whether the continous epidural steroid injection is effective or not.
详细描述
Continous epidural injection will be done during 10 days. D group will be injected a 0.19% ropivacaine 8mL and dexametasone 1mg every other day during 10 days.
Continous epidural injection will be done during 10 days N group will be injected a 0.19% ropivacaine 8mL only every other day during 10 days
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who has herpes zoster
- •Patients has a period (at least 1month) after onset of herpes zoster
- •Patients has a definite symptom along dermatome
- •ASA class I - II
- •Age : 18 - 80 years
排除标准
- •Patients who has a cancer
- •Patients who has a neurologic, psychologic, renal, hepatic and hematologic disease
- •Patients who has a other dermatologic disease
- •Patients who has major operation & procedure history
- •Patients who has a other pain origin
- •Patients who can not be inserted epidural catheter
研究组 & 干预措施
D group
0.19% Ropivacaine 8mL + Dexametasone 1mg every other day injection during 10 days
干预措施: Dexamethasone (Drug)
D group
0.19% Ropivacaine 8mL + Dexametasone 1mg every other day injection during 10 days
干预措施: Ropivacaine (Drug)
N group
0.19% Ropivacaine 8mL only every other day injection during 10 days
干预措施: Ropivacaine (Drug)
结局指标
主要结局
VAS score
时间窗: up to 10 days
The investigator set the primary outcome If there is a 50% reduction of VAS score.
次要结局
未报告次要终点
研究者
Jung Eun Kim
Assistant professor
Korea University Guro Hospital