Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 160
- 主要终点
- Change from Baseline in neurocognitive performance from baseline to post-intervention, relative to change observed during the 8-week wait-list period (Screen for Cognitive Impairment in Psychiatry)
研究概览
简要总结
Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning. These impairments can cause significant distress and disrupt daily functioning by preventing individuals from actively participating in school or work, maintaining healthy relationships with others, and engaging in everyday activities independently. The goal of this clinical trial is to examine if action-based cognitive remediation (ABCR) therapy, a type of cognitive training program, works to treat cognitive impairments in participants with psychiatric disorders.
The main questions it aims to answer are:
- Whether the intervention will improve the thinking skills of participants with different types of psychiatric conditions
- Whether the intervention will improve social skills and work performance
- Can this program be easily used in a regular hospital, and do the people who take part in it find it helpful and worth their time
- Whether the improvements from the intervention last for a long time after the training is over.
Researchers will compare how much the thinking skills of participants change during an 8-week waiting period (where they get no treatment) to how much they change during the 8-week training program to see if the training makes a bigger difference in helping them think and live better.
Participants will :
- Complete a series of questionnaires on memory, thinking skills, and mental health at the beginning of the study
- Wait 8 weeks without any intervention or training
- Complete the series of questionnaires again
- Complete an 8-week training intervention of ABCR where they will use special computer programs to practice real-life skills and tasks like planning a meal or making an appointment
- Complete the series of questionnaires and an additional structured interview to assess acceptability and feasibility of the intervention.
- 3 month later, complete questionnaires for a final time.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants must have been given a diagnosis of a psychiatric disorder (such as mood anxiety, psychotic disorders, etc.
- •Participants must have reported subjective cognitive difficulties associated with their psychiatric disorder
- •Participants must be capable of providing informed consent
- •Participants must have the ability to speak and read in either English or French
- •Participants must have no changes to their medication intake (such as starting or stopping medication or changing doses) within the past month before providing consent for participation
排除标准
- •Participants will be excluded if they are hospitalized at the time of recruitment
- •Participants will be excluded if they have a confirmed diagnosis of an intellectual disability
研究组 & 干预措施
Action-Based Cognitive Remediation (ABCR) with Waitlist Control Period
干预措施: Action-Based Cognitive Remediation (Behavioral)
结局指标
主要结局
Change from Baseline in neurocognitive performance from baseline to post-intervention, relative to change observed during the 8-week wait-list period (Screen for Cognitive Impairment in Psychiatry)
时间窗: Participants complete the Screen for Cognitive Impairment in Psychiatry at baseline, 1 week post-waiting period, 1 week post-intervention, and 3-months post-intervention
Investigators will assess cognitive functioning using the Screen for Cognitive Impairment in Psychiatry, from which a composite score will be calculated to represent overall cognitive performance. The test is comprised of five subscales: the Verbal Learning Test scores range from 0-30, the Working Memory Test scores range from 0-24, the Verbal Fluency scores represent number of correct responses with no fixed maximum score, the Verbal Learning Test-Delayed scores range from 0-10, the Processing Speed Test scores range from 0-30.
次要结局
- Change in Social Cognition from Baseline to Post-Intervention Relative to the 8-Week Wait-List Period (Brief Social Cognition and Emotional Processing)(Participants complete the BSCOPE at baseline, 1 week post-waiting period, 1 week post-intervention, and 3-months post-intervention.)
- Change from Baseline in Community Functioning from Baseline to Post-Intervention, Relative to Change Observed During the 8-Week Wait-List Period (Role Functioning Scale)(Participants complete the Role Functioning Scale at baseline, 1 week post-waiting period, 1 week post-intervention, and 3-months post-intervention.)
- Change from Baseline in Goal Attainment from Baseline to Post-Intervention, Relative to Change Observed During the 8-Week Wait-List Period (Goal Attainment Scaling)(Participants complete Goal Attainment Scaling at baseline, 1 week post-waiting period, 1 week post-intervention, and 3-months post-intervention.)
- Change from Baseline in Social and Occupational Functioning from Baseline to Post-Intervention, Relative to Change Observed During the 8-Week Wait-List Period (Social and Occupational Functioning Assessment Scale)(Participants complete the Social and Occupational Functioning Assessment Scale at baseline, 1 week post-waiting period, 1 week post-intervention, and 3-months post-intervention.)
- Feasibility of the intervention(Participants will conduct a structured interview 1 week-post intervention)
- Acceptability of the intervention(Participants will conduct a structured interview 1 week post-intervention)
研究者
Synthia Guimond
Principal Investigator
The Royal Ottawa Mental Health Centre