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临床试验/RBR-5qkn8h
RBR-5qkn8h招募中4 期

Effect of diuretic combination in patients with acutely decompensated heart failure - a randomized clinical trial

Hospital de Clínicas de Porto Alegre0 个研究点开始时间: 2019年7月23日最近更新:
适应症

试验速览

阶段
4 期
状态
招募中
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Intervention

入排标准

年龄范围
18Y 至 99Y(—)

入选标准

  • Diagnosis of acutely decompensated heart failure; age greater than 18 years; male and female; emergency admission for less than 18 hours; signs of congestion (lower limb edema, pulmonary crackles, chest X-ray with signs of congestion, jugular swelling or hepatojugular reflux, weight gain greater than 4.5 kg); endogenous creatinine clearance greater than 30 ml / min; serum potassium between 3.5 and 5.1 mEq / L; ejection fraction equal to or less than 45% in the last 12 months; to sign a free and informed consent form.

排除标准

  • Hypernatremia; Bartter or Gitelman syndrome; renal tubular acidosis type IV; allergy to sulfa; validity of acute coronary syndrome; history of gout; gestation or lactation; septic shock; hepatic dysfunction (elevation of transaminases three times the reference value); inability to enteral intake.

研究者

发起方
Hospital de Clínicas de Porto Alegre

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